Category Archives: Lab Members

This sections shows all the lab members.

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Robert Schmieder

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Location: GMCS 429

Phone: +1 619 594-3137

Email: rschmied@sciences.sdsu.edu

Robert’s lab blog

 

Research

I started in the PhD program in Computational Sciences at SDSU in fall 2008. Since then, I have been working on the development of tools related to metagenomics (genomic analysis of all microorganisms present in a specific habitat) and environmental studies. The Computational Sciences program supports the collaboration between computer scientists and applied sciences, such as Biology. As part of the program, I worked in the laboratory of Dr. Forest Rohwer to extend my training in laboratory methods and now I apply this knowledge to my computational work, analyzing data sets and developing tools for their automatic analysis.

I implemented several programs for the analysis of microbial community samples for the ease of use by biologists, especially those performing specialized analyses in our collaborator’s labs. Additionally, I work on the analysis of metagenomic data from a wide variety of samples including mosquitoes, cystic fibrosis patients, and coral reefs.

 

Education
  • PhD Student (since 2008), Computational Science Research Center, SDSU, San Diego, CA
  • Master of Science in Bioinformatics and Genome Research, 2007 (Bielefeld University, Bielefeld, Germany)
  • Bachelor of Science in Bioinformatics and Genome Research, 2005 (Bielefeld University, Bielefeld, Germany)

More details about my professional and educational background can be found here.

 

Publications

    An up-to-date list of my publications can be found at Google Scholar (http://bit.ly/robpubl).

    wordle could of publications
    My publications in 100 words (Thanks to wordle.net)

     

    Tools

    Some of the tools I developed as part of my research:

    logo_prinseq logo_tagcleaner logo_deconseq logo_riboPicker
    Awards
    • BiCi Leonardo Melandri Program for Bertinoro Computational Biology 2012
    • Inamori Fellowship, Fall 2011 and Spring 2012
    • First Place in Lavine VentureStart Competition, 2011
    • Travel Grant for International Human Microbiome Congress, 2011
    • Instructionally Related Activities (IRA) Travel Grant, 2010
    • Travel Grant for Human Microbiome Research Conference, 2010
    • Merit Award for poster presentation at 7th annual ACSESS meeting, 2010
    • CGU Fellowship – Math, Fall 2009 and Spring 2010
    • Claremont Graduate University Travel Award for microbial community-profiling project on Curaçao, Netherlands Antilles, 2009
    • California State University Program for Education and Research in Biotechnology (CSUPERB) Travel Grant Award, 2009
    • Instructionally Related Activities (IRA) Travel Grant for ISMB/ECCB 2009
    • Student Travel Grant at Metagenomics 2008
    • German Academic Exchange Service (DAAD) Study Abroad Scholarship, 2007

     

    Presentations

    Oral:

    • Bertinoro Computational Biology Meeting, Bertinoro, Italy, 2012
    • TSRC Cystic Fibrosis Meeting, Telluride, CO, 2011
    • Student Research Symposium (SRS), San Diego, CA, 2010
    • Student Research Symposium (SRS), San Diego, CA, 2009

    Workshop:

    • Bioinformatics for metagenomics, Ensenada, Mexico, 2010

    Poster:

    • International Human Microbiome Congress (IHMC), Paris, France, 2012
    • San Diego Microbiology Group (SDMG) All-day meeting, San Diego, CA, 2012
    • Student Research Symposium (SRS), San Diego, CA, 2012
    • Advances in Genome Biology & Technology (AGBT), Marco Island, FL, 2012
    • International Human Microbiome Congress (IHMC), Vancouver, Canada, 2011
    • San Diego Microbiology Group (SDMG) All-day meeting, San Diego, CA, 2011
    • Student Research Symposium (SRS), San Diego, CA, 2011
    • Microbiome Studies @ Pacific Symposium on Biocomputing (PSB), Big Island of Hawaii, 2011
    • Rocky Mountain Bioinformatics Conference, Aspen/Snowmass, CO, 2010
    • Human Microbiome Research Conference, St Louis, MO, 2010
    • General meeting of the American Society for Microbiology (ASM), San Diego, CA, 2010
    • San Diego Microbiology Group (SDMG) All-day meeting, San Diego, CA, 2010
    • Applied Computational Science and Engineering Student Support (ACSESS), San Diego, CA, 2010
    • Metagenomics, Metadata, and Metaanalysis (M3), Sweden, 2009
    • Intelligent Systems for Molecular Biology/European Conference on Computational Biology (ISMB/ECCB), Sweden, 2009
    • Applied Computational Science and Engineering Student Support (ACSESS), San Diego, CA, 2009
    • San Diego Microbiology Group (SDMG) All-day meeting, San Diego, CA, 2009
    • 3rd Annual International Conference on Metagenomics, San Diego, CA, 2008
    • International Coral Reef Symposium (ICRS), Fort Lauderdale, FL, 2008
    • Student Research Symposium (SRS), San Diego, CA, 2008
    • San Diego Microbiology Group (SDMG) All-day meeting, San Diego, CA, 2008
    • Applied Computational Science and Engineering Student Support (ACSESS), San Diego, CA, 2008
    Sajia Akhter

    Sajia Akhter

    Sajia Akhter space

    Location: GMCS 429

    Phone: +1 619 594-3137

    Email: sakhter@sciences.sdsu.edu

    Sajia’s lab blog

    Bio
    I am a Ph.D. student in Computational Science Research Center (CSRC) at SDSU. I have joined the lab in Fall, 2007.
    Research
    Currently, I am working on sequence alignment. The goal of this project is to develop a local sequence alignment tool for both DNA and protein sequences, which will work faster than contemporary tools but will give the same or better accuracy.

    I have also designed a phage detection algorithm (PhiSpy) for identifying known and undefined prophages in microbial genomes. In PhiSpy, seven distinctive characteristics of prophages are used to predict prophages. These characteristics are protein length, transcription strand directionality, customized AT and GC skew, the abundance of unique phage words, phage insertion points and the similarity of phage proteins.

    In the past I worked on applying the information theory on metagenomics and microbial community. I have found that the information theory can be effectively applied on finding informative sequences.
    Education
    • PhD Student, Computational Science Research Center, SDSU, (started in Fall 07)
    • Bachelor of Science in Computer Science – Summa Cum Laude, American International university-Bangladesh (AIUB), Bangladesh, 2007. I have achieved the Vice Chancellor Award for the Best Thesis in Computer Science.
    Publications
    • Sajia Akhter; Ramy K. Aziz; Robert A. Edwards. PhiSpy: a novel algorithm for finding prophages in bacterial genomes that combines similarity- and composition-based strategies, 2012 Nucleic Acids Research doi: 10.1093/nar/gks406
    • Hedin M, Starrett J, Akhter S, Schönhofer AL, Shultz JW. Phylogenomic Resolution of Paleozoic Divergences in Harvestmen (Arachnida, Opiliones) via Analysis of Next-Generation Transcriptome Data, 2012 PLoS ONE 7(8): e42888. doi:10.1371/journal.pone.0042888
    • Noriko Cassman, Alejandra Prieto-Davó, Kevin Walsh, Genivaldo G. Z. Silva, Florent Angly, Sajia Akhter, Katie Barott, Julia Busch, Tracey McDole, J. Matthew Haggerty, Dana Willner, Gadiel Alarcón, Osvaldo Ulloa, Edward F. DeLong, Bas Dulith, Forest Rohwer, Elizabeth A. Dinsdale. Oxygen minimum zones harbor novel viral communities with low diversity. Environmental Microbiology 2012 [Accepted]
    • Terry Disz, Sajia Akhter, Daniel Cuevas, Robert Olson, Ross Overbeek, Veronika Vonstein, Rick Stevens and Robert Edwards, Accessing the SEED Genome Databases via Web Services API: Tools for Programmers 2010 BMC Bioinformatics 11:319 doi:10.1186/1471-2105-11-319.
    • Sajia Akhter, Ipshita Sarkar, Kazi Golam Rabbany, Nahid Akter, Shamim Akhter, Yann Chemin and Honda Kiyoshi, Adapting the LMF Temporal Splining Procedure From Serial to MPI/Linux Clusters, 2007 Journal of Computer Science 3(3): 130-133, Science Publication, New York, USA.

    Posters
    • Sajia Akhter, Robert Edwards, Tools fot fast sequence alignment, Student Research Symposium, SRS, San diego State University, San Diego, CA, 2012
    • Sajia Akhter, Anca Segall, Molly Schmid, Robert Edwards, Investigating Quinolone Resistance Sequences in Environmental Samples, General meeting of the American Society for Microbiology (ASM), San Diego, CA, 2010
    • Sajia Akhter, Robert Edwards, Assembler for SoLiD data: Improving the memory management of Velvet assembler, 7th Rocky Mountain Bioinformatics Conference, Aspen, Colorado, 2009
    • Sajia Akhter, Barbara Bailey, Peter Salamon, and Robert Edwards, Shannon’s Uncertainty and Kullback-Leibler Divergence in Microbial Genome and Metagenome Sequences, Poster Session, 1st International Conference on Bioinformatics and Computational Biology (BICoB), 2009

    space

    Sajia Akhter

    Sajia Akhter space

    Location: GMCS 429

    Phone: +1 619 594-3137

    Email: sakhter@sciences.sdsu.edu

    Sajia’s lab blog

    Bio
    I am a Ph.D. student in Computational Science Research Center (CSRC) at SDSU. I joined the lab in Fall, 2007.
    Research
    Currently, I am working on identifying prophages. Based on different properties of phages, I am developing an algorithm, which can determine known and unknown prophages in a bacterial genome.
    I also conduct my research on the assembly problem – especially designing efficient assembler for very short sequences (SOLiD/Solexa). In the past I worked on applying the information theory on metagenomics and microbial community. I have found that the information theory can be effectively applied on finding informative sequences.
    Education
    • PhD Student, Computational Science Research Center, SDSU, (started in Fall 07)
    • Bachelor of Science in Computer Science – Summa Cum Laude, American International university-Bangladesh (AIUB), Bangladesh, 2006. I have achieved the Vice Chancellor Award for the Best Thesis in Computer Science.
    Publications
    • Terry Disz, Sajia Akhter, Daniel Cuevas, Robert Olson, Ross Overbeek, Veronika Vonstein, Rick Stevens and Robert Edwards, Accessing the SEED Genome Databases via Web Services API: Tools for Programmers, Accepted in BMC Bioinformatics 2010.
    • Sajia Akhter, Ipshita Sarkar, Kazi Golam Rabbany, Nahid Akter, Shamim Akhter, Yann Chemin and Honda Kiyoshi, Adapting the LMF Temporal Splining Procedure From Serial to MPI/Linux Clusters, Journal of Computer Science 3(3): 130-133, 2007, Science Publication, New York, USA.

    Posters
    • Sajia Akhter, Anca Segall, Molly Schmid, Robert Edwards, Investigating Quinolone Resistance Sequences in Environmental Samples, General meeting of the American Society for Microbiology (ASM), San Diego, CA, 2010
    • Sajia Akhter, Robert Edwards, Assembler for SoLiD data: Improving the memory management of Velvet assembler, 7th Rocky Mountain Bioinformatics Conference, Aspen, Colorado, 2009
    • Sajia Akhter, Barbara Bailey, Peter Salamon, and Robert Edwards, Shannon’s Uncertainty and Kullback-Leibler Divergence in Microbial Genome and Metagenome Sequences, Poster Session, 1st International Conference on Bioinformatics and Computational Biology (BICoB), 2009

    Ramy K. Aziz

    space

    Postgraduate Researcher at Edwards Lab (2008-2011)

    Current location: UCSD Bioengineering 426

    Phone: +1 (858) 822 1144

    Email: raziz1ATgmailDOTcom

    Ramy’s section in Edwards Lab Blog

    on Twitter (azizrk); Scholar; Mendeley; Researcher ID: B-2918-2009

    Other blogs:

    Bio (updated on 11/11/11)

    Ramy finds it weird to refer to himself in the third person and thinks that bios written in third person—like many other aspects of scientific writing—are pretentious because they are almost always written by the “first person.” Thus, I will write my bio using the first person “I.”

    Position

    – I am currently a Visiting Scientist at UCSD’s Systems Biology Research Group (AKA Palsson lab). I also hold a tenured Assistant Professor position in the Department of Microbiology, Faculty of Pharmacy, Cairo University (FOPCU).

    – I have been in-and-out the Edwards lab between April 2008 and September 2011. During that period, though, my position (or affiliation) and my physical position (location) have changed a few times.  One of the most common questions I get asked is: “where are you exactly working?” The right answer is: online!

    • When I joined the lab, I was first appointed as an adjunct faculty member at the Computational Science Research Center of SDSU, a position which I still hold. In July 2008, I was appointed by the University of Chicago as a Research Associate (to work on the NMPDR project while physically at SDSU) then, between July 2009-2011, as a Research Associate at SDSU, instead.
    • Between 2008 and 2011, I was also a lecturer (i.e., a tenured junior faculty member involved in teaching and conducting research without taking primary credit for it) in the Department of Microbiology and Immunology at FOPCU. I actually got this position in July 2006. As a lecturer, I taught microbiology and immunology to undergraduate and graduate students between 2006-2008. In addition I started a series of workshops between 2006-2010 on bioinformatics, pharmacogenetics/pharmacogenomics, and gene therapy in FOPCU and in the German University in Cairo (GUC). I also supervised or co-supervised a few undergraduate students and six graduate students (one of whom received her PhD in 2008; two received their MS degrees in 2009 and 2010; while three of them are still–more ore less–working on their master’s projects).
    Research
    • My main projects at SDSU were to (i) devlop (better) tools and methods for annotating bacteriophage genomes; (ii) annotate phage genomes using the subsystems technology; and (iii) use these tools and annotations for the interpretation of phage genomes and, by extension, microbial genomes, viral, and microbial metagenomes. More details can be found in the Phage Annotation Tools and Methods (PhAnToMe) website.
    • My broader research interests are in the evolution of virulence in bacteria (but also in other pathogenic organisms like archaea, unicellular eukaryotes, and Homo sapiens). Because bacterial virulence, like many other bacterial phenotypes, is contributed by bacteriophages, viruses that infect bacteria, I got interested into studying bacteriophages as well. During my PhD project and my first postdoctoral training, I have discovered a variant of a bacterial toxin (streptodornase 1) encoded by a bacteriophage that resides in the genome of the human-restricted pathogen Streptococcus pyogenes (a.k.a. Strep). Strep causes sore throat, pharyngitis, and skin diseases, but can turn into a killer monster (a.k.a. flesh-eating bacteria).
    • Finally, I am also interested in several topics that came out of the studies mentioned above. These inclue immunogenetics (how different animals and humans react differently to bacterial infections), reconstructing bacterial virulomes from genomic data, and integrating diverse microarray data to improve the biological relevance of their interpretation.
    Education
    Rob Edwards

    Rob Edwards

    Office: BIO 231

    Lab: BIO 212

    Phone: +61 8 8201 3417

    Email: robert.edwards@flinders.edu.au

    Some photos of Rob

    Robert Edwards – Biography

    After receiving his Ph. D. from the University of Sussex, in England studying nitrogen regulation in bacteria, Dr. Edwards moved to the United States to continue his studies. He worked as a Post-Doctoral Researcher at the University of Pennsylvania, Philadelphia, understanding how a leading cause of traveller’s diarrhea (E. coli)causes disease. Dr. Edwards then moved to the University of Illinois, Urbana Champaign to study another food-borne pathogen, Salmonella. These studies merged the nascent area of genomics with traditional microbial genetics to investigate how a particular type of Salmonella became the leading cause of food-borne illness in the United States.

    From 2000 to 2004, Dr. Edwards was an Assistant Professor at the University of Tennessee Health Sciences Center in Memphis, TN. Here, Dr. Edwards continued his studies on pathogenic bacteria, notably Salmonella and the bioterrorism weapon Francisella. Dr. Edwards received FBI clearance to work on these bacteria and was invited to the NIH to comment on the use of Select Agents at basic research laboratories.

    In 2004, Dr. Edwards moved to the non-profit Fellowship for Interpretation of Genomes to work at the interface of biologists and computer scientists and worked with their team at Argonne National Laboratory. He remains an active software developer for Argonne and the Fellowship, developing open-source software including PERL and Python software for biological analysis and parallel computing that are used by scientists worldwide. Using breakout DNA sequencing technologies, Dr. Edwards’ studies have continually pushed the forefront of both sequencing technology and bioinformatics. His work has been published in leading journals including multiple papers in both Nature and Science.

    Dr. Edwards returned to academia in 2007, taking a research and teaching position in the Departments of Computer Science and Biology at San Diego State University where he rose through the ranks to become a Full Professor. He continued to work at the interface of biology and computing.  The National Institutes of Health, the National Science Foundation, the Department of Education, the Department of Defense, the USGS, and private donors funded Dr. Edwards’ research at SDSU, and his work led to breakthroughs in our understanding of how viruses interact with their hosts, and how viruses from around the world carry important genetic information. Dr. Edwards has continued to push current sequencing and bioinformatics technologies, in 2013 took a next-generation sequencing machine to the remote Southern Line Islands to explore metagenomics of coral reefs in real-time. In 2014 Dr. Edwards’ team identified a virus that is present in the intestines of approximately half the people in the world, and in 2019 Dr. Edwards demonstrated the global spread of the virus in a paper that includes collaborators from every continent who collected and sequenced samples. In 2017, Dr. Edwards was elected to the American Academy of Microbiology in recognition of his contributions to the field of microbiology. In 2020, Dr. Edwards took the position of Matthew Flinders Fellow in Bioinformatics at Flinders University, in Adelaide, South Australia, Australia to start the Flinders Accelerator for Microbiome Exploration, to enhance microbiome and metagenome studies in South Australia.

    Committed to teaching, Dr. Edwards received the graduate student award for the outstanding educator at the University of Tennessee, the teacher-scholar award and outstanding faculty award four times at San Diego State University. He was Graduate Advisor to the Biological and Medical Informatics Program at SDSU. Rob travels extensively to share his passion for bioinformatics and has taught bioinformatics classes around the US, and in Australia, China, Chile, Europe, Mexico, and North and South America. Dr. Edwards holds a visiting professor position at the Federal University of Rio de Janeiro.

    In addition to science and teaching Dr. Edwards is also an advanced scientific SCUBA diver having led teams to study Coral Reefs all over the world. In his spare time, he is an avid international yachtsman, navigating in long-distance offshore races, including navigating the 2019 TransPac race from Los Angeles to Honolulu finishing 4th out of 89 boats.

    Rob Edwards

    Lab members

    Principal Investigator
    Rob Edwards

     

     Postgraduate Researchers
    Jeremy Frank
    Dave Matthews

     

    PhD Students
    Rob S

     

    Master Students
    Adam

    Katelyn McNair

    Steven Williams

    Sheridan

    Undergraduate Students
    Palla
    Heqiao

    Blaire Robinson

    Visiting Researchers

     

    Lab Alumni

    Brian Hudson

    Ramy Aziz
    Andres
    nick
    carny

    bas
    stephanie
    Matthew
    brad
    ben
    Huy
    Amanda Trindade
    Thiago Bruce
    Promita Bose
    Vasken Kamiksisian
    Vasken Kamiksisian
    Joakim
    Matt Seitz
    Matt Seitz
    Rima Soury

     

    Master students

    Nick Celms

     image Cool

    Email:  
    Phone:  

    Nick Celms has been part of the Edwards lab since the Summer of 2008, and works on visualizations of BLAST comparisons. He spent his first two years as an undergraduate at the University of Washington before transferring to San Diego State’s computer science department. Nick is one of SDSU’s first wave of cross-trained students participating in the BioMath program, an emerging NSF priority. Outside the lab, Nick is the Vice President of a student organization called Compassion for African Villages that sends aide to the village of Rundongo, Zimbabwe.

     

    Carny Cheng

    image Surprised

    Email:  
    Phone:  

    Carny is a Computational Science Masters student. His research focuses mainly on web services providing middleware for scientists to access cyberinfrastructure resources. Carny holds two Bachelors degrees from University of California, San Diego in Computer Engineering and economics. He has spent sometime working in the software industry at Websense, Inc. where he bounced from project to project eventually settling in text classification.

    Carny also serves as the lab system administrator. It is advisable to stay on Carny’s good-side if you want your access to the lab’s computing resources.

     

    Kate McNair

    image Surprised

    Email:  
    Phone:  

    Kate is a …