If you see the error
samtools: error while loading shared libraries: libcrypto.so.1.0.0: cannot open shared object file: No such file or directory it is probably a
As of the time of writing,
samtools version 1.7, but
samtools 1.14 is available, and there were some significant changes around version 1.9 that changed the SSL libraries samtools uses.
mamba uninstall samtools
This will tell you what depends on
samtools, and it will remove it too! If your
samtools is an earlier version, then you will also see that here.
mamba install samtools
Now you are up to date. Once you have confirmed this version of
samtools works, you can try installing the offending package (that was removed alongside
samtools) and see it tries to downgrade your
samtools version. For me, that was